DISCOVERY team

  1. 2013
  2. Published

    Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

    Bertin, G. I., Lavstsen, Thomas, Guillonneau, F., Doritchamou, J., Wang, Christian William, Jespersen, Jakob Schmidt, Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, Thor Grundtvig & Deloron, P., 2013, In: P L o S One. 8, 7, p. e68368

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2012
  5. Published

    Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

    Lavstsen, Thomas, Turner, Louise, Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, Jakob Schmidt, Wang, Christian William, Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, Eske, Gilbert, M Thomas P, Lusingu, J. P. A. & Theander, Thor Grundtvig, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

    Claessens, A., Adams, Y., Ghumra, A., Lindergard, G., Buchan, C. C., Andisi, C., Bull, P. C., Mok, S., Gupta, A. P., Wang, Christian William, Turner, Louise, Arman, M., Raza, A., Bozdech, Z. & Rowe, J. A., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1772-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1

    Wang, Christian William, Lavstsen, Thomas, Bengtsson, D. C., Magistrado, P. A., Berger, S. S., Marquard, A. M., Alifrangis, Michael, Lusingu, J. P., Theander, Thor Grundtvig & Turner, Louise, 2012, In: Malaria Journal. 11, 1, p. 129

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes

    Mwakalinga, S. B., Wang, Christian William, Bengtsson, D. C., Turner, Louise, Dinko, B., Lusingu, J. P., Arnot, D. E., Sutherland, C. J., Theander, Thor Grundtvig & Lavstsen, Thomas, 2012, In: Malaria Journal. 11, 1, p. 429

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2011
  10. Published

    Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

    Bejon, P., Turner, Louise, Lavstsen, Thomas, Cham, G., Olotu, A., Drakeley, C. J., Lievens, M., Vekemans, J., Savarese, B., Lusingu, J., von Seidlein, L., Bull, P. C., Marsh, K. & Theander, Thor Grundtvig, 1 Jan 2011, In: P L o S One. 6, 6, p. e21711

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

    Turner, Louise, Wang, Christian William, Lavstsen, Thomas, Mwakalinga, S. B., Sauerwein, R. W., Hermsen, C. C. & Theander, Thor Grundtvig, 2011, In: P L o S One. 6, 12, p. e29025

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

    Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2010
  14. Published

    Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer

    Rask, T. S., Hansen, D. A., Theander, Thor Grundtvig, Gorm Pedersen, A. & Lavstsen, Thomas, 2010, In: P L o S Computational Biology. 6, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

    Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum

    Wang, Christian William, Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, Thor Grundtvig & Lavstsen, Thomas, 2010, In: Malaria Journal. 9, 1, p. 147

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Macrogeographical variability in the great call of Hylobates agilis: assessing the applicability of vocal analysis in studies of fine-scale taxonomy of gibbons

    Heller, Rasmus, Sander, Adam F. , Wang, Christian William, Usman, F. & Dabelsteen, Torben, 2010, In: American Journal of Primatology. 72, 2, p. 142-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

    Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2009
  20. Published

    An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

    Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites

    Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

    Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

    Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

    Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

    Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer

    Wang, Christian William, Hermsen, C. C., Sauerwein, R. W., Arnot, D. E., Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: Parasitology International. 58, 4, p. 478-80 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2008
  28. Published

    Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression

    Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

    Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

    Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2007
  32. Published

    3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity

    Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review