- 2024
- Published
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, Helle Smedegaard, Hocke, Emma Filtenborg, Gilberger, T. W., Duffy, M. F., Lavstsen, Thomas, Baum, J., Otto, T. D., Cunnington, A. J. & Bachmann, A., 25 Jan 2024, In: eLife. 12, 38 p., RP87726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contact allergens in African countries: A review of published patch test studies
Bonefeld, N. M., Menné, T., Ahrensbøll-Friis, U., Gadsbøll, A. S. Ø., Wang, Christian William, Theander, Thor Grundtvig, Masenga, E. J., Mavura, D., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2024, In: Contact Dermatitis. 90, 2, p. 103-109Research output: Contribution to journal › Review › Research › peer-review
- 2023
- Published
Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana
Ahorhorlu, S. Y., Quashie, N. B., Jensen, R. W., Kudzi, W., Nartey, E. T., Duah-Quashie, N. O., Zoiku, F., Dzudzor, B., Wang, Christian William, Hansson, Helle Smedegaard, Alifrangis, Michael & Adjei, G. O., 2023, In: Malaria Journal. 22, 58.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Ad19a/64 HERV-W Vaccines Uncover Immunosuppression Domain-Dependent T-Cell Response Differences in Inbred Mice
Skandorff, I., Ragonnaud, Emeline, Gille, J., Andersson, A. M., Schrödel, S., Duvnjak, Lara, Turner, Louise, Thirion, C., Wagner, R. & Holst, Peter Johannes, 2023, In: International Journal of Molecular Sciences. 24, 12, 9972.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Analysis of var gene transcript patterns by quantitative real-time PCR
Bachmann, A. & Lavstsen, Thomas, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 149–171 23 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Mapping the cord blood transcriptome of pregnancies affected by early maternal anemia to identify signatures of fetal programming
Hatem, G., Hjort, Line, Asplund, O., Minja, D. T. R., Msemo, O. A., Møller, S. L., Lavstsen, Thomas, Grunnet, Louise Groth, Lusingu, J. P. A., Hansson, O., Christensen, Dirk Lund, Vaag, Allan, Artner, I., Theander, Thor Grundtvig, Groop, L., Schmiegelow, Christentze, Bygbjerg, Ib Christian & Prasad, R. B., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 5, p. 1303–1316 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seroprevalence of SARS-CoV-2 antibodies among children and adolescents recruited in a malariometric survey in north-eastern Tanzania July 2021
Lyimo, E., Fougeroux, Cyrielle Elyette, Malabeja, A., Mbwana, J., Hayuma, P. M., Liheluka, E., Turner, Louise, Gesase, S., Lavstsen, Thomas, Lusingu, J. P. A., Minja, D. T. R. & Wang, Christian William, 2022, In: BMC Infectious Diseases. 22, 846.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Varia: a tool for prediction, analysis and visualisation of variable genes
Mackenzie, G., Jensen, R. W., Lavstsen, Thomas & Otto, T. D., 2022, In: BMC Bioinformatics. 23, 13 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Complement C1s cleaves PfEMP1 at interdomain conserved sites inhibiting Plasmodium falciparum cytoadherence
Azasi, Y., Low, L. M., Just, A. N., Raghavan, Sai Sundar Rajan, Wang, Christian William, Valenzuela-Leon, P., Alexandra Rowe, J., Smith, J. D., Lavstsen, Thomas, Turner, Louise, Calvo, E. & Miller, L. H., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 22, e2104166118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-guided design of a synthetic mimic of an endothelial protein C receptor-binding PfEMP1 protein
Barber, N. M., Lau, C. K. Y., Turner, Louise, Watson, G., Thrane, Susan, Lusingu, J. P. A., Lavstsen, Thomas & Higgins, M. K., 2021, In: mSphere. 6, 1, 14 p., e01081-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of asymptomatic malaria, submicroscopic parasitaemia and anaemia in Korogwe District, north-eastern Tanzania
Hayuma, P. M., Wang, Christian William, Liheluka, E., Baraka, V., Madebe, R. A., Minja, D. T. R., Misinzo, G., Alifrangis, Michael & Lusingu, J. P. A., 2021, In: Malaria Journal. 20, 9 p., 424.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ten years of monitoring malaria trend and factors associated with malaria test positivity rates in Lower Moshi
Kassam, N. A., Kaaya, R. D., Damian, D. J., Schmiegelow, Christentze, Kavishe, R. A., Alifrangis, Michael & Wang, Christian William, 2021, In: Malaria Journal. 20, 1, 193.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of anti-gSG6-P1 IgG as a serological biomarker to assess temporal exposure to Anopheles' mosquito bites in Lower Moshi
Kassam, N. A., Kulaya, N., Kaaya, R. D., Schmiegelow, Christentze, Wang, Christian William, Kavishe, R. A. & Alifrangis, Michael, 2021, In: PLoS ONE. 16, 10, e0259131.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations
Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, Helle Smedegaard, Crespo Bravo, Marina, Wang, Christian William, Lusingu, J., Theisen, Michael, Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, Michael, 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes
Petersen, J. E. V., Saelens, J. W., Freedman, E., Turner, Louise, Lavstsen, Thomas, Fairhurst, R. M., Diakité, M. & Taylor, S. M., 2021, In: P L o S Pathogens. 17, 6, 18 p., e1009659.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common virulence gene expression in adult first-time infected malaria patients and severe cases
Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., von Thien, H., Scholz, J. A. M., Smedegaard Hansson, H., Weisel Jensen, R., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., D Otto, T., Lavstsen, T., Gilberger, T. W., Duffy, M. & 1 others, , 2021, In: eLife. 10, e69040.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season
Andrade, C. M., Fleckenstein, H., Thomson-Luque, R., Doumbo, S., Lima, N. F., Anderson, C., Hibbert, J., Hopp, C. S., Tran, T. M., Li, S., Niangaly, M., Cisse, H., Doumtabe, D., Skinner, J., Sturdevant, D., Ricklefs, S., Virtaneva, K., Asghar, M., Homann, M. V., Turner, L. & 17 others, , 2020, In: Nature Medicine. 26, p. 1929–1940Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a conserved var gene in different Plasmodium falciparum strains
Dimonte, S., Bruske, E. I., Enderes, C., Otto, T. D., Turner, Louise, Kremsner, P. & Frank, M., 2020, In: Malaria Journal. 19, 1, 15 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies
Harmsen, C., Turner, Louise, Thrane, Susan, Sander, Adam F. , Theander, Thor Grundtvig & Lavstsen, Thomas, 2020, In: Malaria Journal. 19, 1, 11 p., 132.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo imaging of the buccal mucosa shows loss of the endothelial glycocalyx and perivascular hemorrhages in pediatric Plasmodium falciparum malaria
Lyimo, E., Haslund, L. E., Ramsing, T., Wang, Christian William, Efunshile, A. M., Manjurano, A., Makene, V., Lusingu, J., Theander, Thor Grundtvig, Kurtzhals, Jørgen, Paulsen, R. & Hempel, C., 2020, In: Infection and Immunity. 88, 3, e00679-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of PfEMP1 Antibody Profile From Birth to 12 Months of Age in Beninese Infants
Moussiliou, A., Turner, Louise, Cottrell, G., Doritchamou, J., Gbédandé, K., Fievet, N., Luty, A. J. F., Massougbodji, A., Theander, Thor Grundtvig, Deloron, P., Lavstsen, Thomas & Tuikue Ndam, N., 2020, In: The Journal of Infectious Diseases. 221, 12, p. 2010-2017 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal analysis of naturally acquired PfEMP1 CIDR domain variant antibodies identifies associations with malaria protection
Obeng-Adjei, N., Larremore, D. B., Turner, Louise, Ongoiba, A., Li, S., Doumbo, S., Yazew, T. B., Kayentao, K., Miller, L. H., Traore, B., Pierce, S. K., Buckee, C. O., Lavstsen, Thomas, Crompton, P. D. & Tran, T. M., 2020, In: JCI Insight. 5, 12, 15 p., e137262.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
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Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa
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Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
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Latest publications
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Research output: Contribution to journal › Journal article › Research › peer-review
Contact allergens in African countries: A review of published patch test studies
Research output: Contribution to journal › Review › Research › peer-review
Human Ad19a/64 HERV-W Vaccines Uncover Immunosuppression Domain-Dependent T-Cell Response Differences in Inbred Mice
Research output: Contribution to journal › Journal article › Research › peer-review