DISCOVERY team

  1. Published

    Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1

    Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Acquisition of antibodies against endothelial protein C receptor-binding domains of Plasmodium falciparum erythrocyte membrane protein 1 in children with severe malaria

    Rambhatla, J. S., Turner, Louise, Manning, L., Laman, M., Davis, T. M. E., Beeson, J. G., Mueller, I., Warrel, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Rogerson, S. J., 2019, In: The Journal of Infectious Diseases. 219, 5, p. 808-818 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer

    Rask, T. S., Hansen, D. A., Theander, Thor Grundtvig, Gorm Pedersen, A. & Lavstsen, Thomas, 2010, In: P L o S Computational Biology. 6, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites

    Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

    Saito, F., Hirayasu, K., Satoh, T., Wang, Christian William, Lusingu, J., Arimori, T., Shida, K., Palacpac, N. M. Q., Itagaki, S., Iwanaga, S., Takashima, E., Tsuboi, T., Kohyama, M., Suenaga, T., Colonna, M., Takagi, J., Lavstsen, Thomas, Horii, T. & Arase, H., 7 Dec 2017, In: Nature. 552, 7683, p. 101-105 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  6. Published

    Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

    Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

    Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

    Shabani, E., Hanisch, B., Opoka, R. O., Lavstsen, Thomas & John, C. C., 2017, In: BMC Medicine. 15, 1, 14 p., 183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

    Shabani, E., Opoka, R. O., Bangirana, P., Park, G. S., Vercellotti, G. M., Guan, W., Hodges, J. S., Lavstsen, Thomas & John, C. C., 3 Jun 2016, In: Scientific Reports. 6, 11 p., 27084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PLASMODIUM FALCIPARUM PARASITES THAT INFECT RETINOPATHY POSITIVE AND NEGATIVE CEREBRAL MALARIA CHILDREN HAVE SIMILAR TRANSCRIPT ABUNDANCE OF VAR GENES ASSOCIATED WITH SEVERE MALARIA

    Shabani, E., Opoka, R. O., Hanisch, B., Tang, B., Bangirana, P., Lavstsen, Thomas & John, C. C., Nov 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5 suppl., p. 75-75

    Research output: Contribution to journalConference abstract in journalResearchpeer-review