DISCOVERY team

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  1. Published

    Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana

    Ahorhorlu, S. Y., Quashie, N. B., Jensen, R. W., Kudzi, W., Nartey, E. T., Duah-Quashie, N. O., Zoiku, F., Dzudzor, B., Wang, Christian William, Hansson, Helle Smedegaard, Alifrangis, Michael & Adjei, G. O., 2023, In: Malaria Journal. 22, 58.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers

    Almelli, T., Nuel, G., Bischoff, E., Aubouy, A., Elati, M., Wang, Christian William, Dillies, M., Coppée, J., Ayissi, G. N., Basco, L. K., Rogier, C., Ndam, N. T., Deloron, P. & Tahar, R., 2014, In: PloS one. 9, 12, p. e114401

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

    Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season

    Andrade, C. M., Fleckenstein, H., Thomson-Luque, R., Doumbo, S., Lima, N. F., Anderson, C., Hibbert, J., Hopp, C. S., Tran, T. M., Li, S., Niangaly, M., Cisse, H., Doumtabe, D., Skinner, J., Sturdevant, D., Ricklefs, S., Virtaneva, K., Asghar, M., Homann, M. V., Turner, L. & 17 others, Martins, J., Allman, E. L., N’Dri, M. E., Winkler, V., Llinás, M., Lavazec, C., Martens, C., Färnert, A., Kayentao, K., Ongoiba, A., Lavstsen, Thomas, Osório, N. S., Otto, T. D., Recker, M., Traore, B., Crompton, P. D. & Portugal, S., 2020, In: Nature Medicine. 26, p. 1929–1940

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture

    Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, Helle Smedegaard, Hocke, Emma Filtenborg, Gilberger, T. W., Duffy, M. F., Lavstsen, Thomas, Baum, J., Otto, T. D., Cunnington, A. J. & Bachmann, A., 25 Jan 2024, In: eLife. 12, 38 p., RP87726.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Complement C1s cleaves PfEMP1 at interdomain conserved sites inhibiting Plasmodium falciparum cytoadherence

    Azasi, Y., Low, L. M., Just, A. N., Raghavan, Sai Sundar Rajan, Wang, Christian William, Valenzuela-Leon, P., Alexandra Rowe, J., Smith, J. D., Lavstsen, Thomas, Turner, Louise, Calvo, E. & Miller, L. H., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 22, e2104166118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

    Bachmann, A., Bruske, E., Krumkamp, R., Turner, Louise, Wichers, J. S., Petter, M., Held, J., Duffy, M. F., Sim, B. K. L., Hoffman, S. L., Kremsner, P. G., Lell, B., Lavstsen, Thomas, Frank, M., Mordmüller, B. & Tannich, E., 2019, In: PLOS Pathogens. 15, 7, 24 p., e1007906.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Analysis of var gene transcript patterns by quantitative real-time PCR

    Bachmann, A. & Lavstsen, Thomas, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 149–171 23 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  9. Published

    Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa

    Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Structure-guided design of a synthetic mimic of an endothelial protein C receptor-binding PfEMP1 protein

    Barber, N. M., Lau, C. K. Y., Turner, Louise, Watson, G., Thrane, Susan, Lusingu, J. P. A., Lavstsen, Thomas & Higgins, M. K., 2021, In: mSphere. 6, 1, 14 p., e01081-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

    Bejon, P., Turner, Louise, Lavstsen, Thomas, Cham, G., Olotu, A., Drakeley, C. J., Lievens, M., Vekemans, J., Savarese, B., Lusingu, J., von Seidlein, L., Bull, P. C., Marsh, K. & Theander, Thor Grundtvig, 1 Jan 2011, In: P L o S One. 6, 6, p. e21711

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

    Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

    Bertin, G. I., Lavstsen, Thomas, Guillonneau, F., Doritchamou, J., Wang, Christian William, Jespersen, Jakob Schmidt, Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, Thor Grundtvig & Deloron, P., 2013, In: P L o S One. 8, 7, p. e68368

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Contact allergens in African countries: A review of published patch test studies

    Bonefeld, N. M., Menné, T., Ahrensbøll-Friis, U., Gadsbøll, A. S. Ø., Wang, Christian William, Theander, Thor Grundtvig, Masenga, E. J., Mavura, D., Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2024, In: Contact Dermatitis. 90, 2, p. 103-109

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1

    Brown, A., Turner, Louise, Christoffersen, S., Andrews, K. A., Szestak, T., Zhao, Y., Larsen, Sine, Craig, A. G. & Higgins, M. K., 22 Feb 2013, In: Journal of Biological Chemistry. 288, 8, p. 5992-6003 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Plasmodium falciparum-CD36 structure-function relationships defined by ortholog scanning mutagenesis

    Cabrera, A., Neculai, D., Tran, V., Lavstsen, Thomas, Turner, Louise & Kain, K. C., 2019, In: The Journal of Infectious Diseases. 219, 6, p. 945-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

    Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

    Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

    Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

    Claessens, A., Adams, Y., Ghumra, A., Lindergard, G., Buchan, C. C., Andisi, C., Bull, P. C., Mok, S., Gupta, A. P., Wang, Christian William, Turner, Louise, Arman, M., Raza, A., Bozdech, Z. & Rowe, J. A., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1772-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

    Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studies

    Derkach, A., Otim, I., Pfeiffer, R. M., Onabajo, O. O., Legason, I. D., Nabalende, H., Ogwang, M. D., Kerchan, P., Talisuna, A. O., Ayers, L. W., Reynolds, S. J., Nkrumah, F., Neequaye, J., Bhatia, K., Theander, Thor Grundtvig, Prokunina-Olsson, L., Turner, Louise, Goedert, J. J., Lavstsen, Thomas & Mbulaiteye, S. M., 2019, In: EBioMedicine. 39, p. 358-368 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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