Centre for Medical Parasitology

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  1. 2015
  2. Published

    Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant

    Petersen, J. E. V., Bouwens, E. A. M., Tamayo, I., Turner, Louise, Wang, Christian William, Stins, M., Theander, Thor Grundtvig, Hermida, J., Mosnier, L. O. & Lavstsen, Thomas, Nov 2015, In: Thrombosis and Haemostasis. 114, 5, p. 1038-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Quality control of microbiota metagenomics by k-mer analysis

    Plaza Onate, F., Batto, J. M., Juste, C., Fadlallah, J., Fougeroux, Cyrielle Elyette, Gouas, D., Pons, N., Kennedy, S., Levenez, F., Dore, J., Ehrlich, S. D., Gorochov, G. & Larsen, M., 14 Mar 2015, In: BMC Genomics. 16, 1, 183.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Risks of hemolysis in glucose-6-phosphate dehydrogenase deficient infants exposed to chlorproguanil-dapsone, mefloquine and sulfadoxine-pyrimethamine as part of intermittent presumptive treatment of malaria in infants

    Poirot, E., Vittinghoff, E., Ishengoma, D., Alifrangis, Michael, Carneiro, I., Hashim, R., Baraka, V., Mosha, J., Gesase, S., Chandramohan, D. & Gosling, R., 2015, In: PloS one. 10, 11, 13 p., e0142414.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced

    Rieger, H., Yoshikawa, H. Y., Quadt, K., Nielsen, Morten Agertoug, Sanchez, C. P., Salanti, Ali, Tanaka, M. & Lanzer, M., 8 Jan 2015, In: Blood. 125, 2, p. 383-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Multiple Origins of Mutations in the mdr1 Gene—A Putative Marker of Chloroquine Resistance in P. vivax

    Schousboe, M. L., Ranjitkar, S., Rajakaruna, R. S., Amerasinghe, P. H., Morales, F., Pearce, R., Ord, R., Leslie, T., Rowland, M., Gadalla, N. B., Konradsen, Flemming, Bygbjerg, Ib Christian, Roper, C. & Alifrangis, Michael, Nov 2015, In: P L o S Neglected Tropical Diseases (Online). 9, 11, 17 p., e0004196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

    Singh, S. K., Roeffen, W., Andersen, G., Bousema, T., Christiansen, M., Sauerwein, R. & Theisen, Michael, 15 Apr 2015, In: Vaccine. 33, 16, p. 1981-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A non-inferiority, individually randomized trial of intermittent screening and treatment versus intermittent preventive treatment in the control of malaria in pregnancy

    Tagbor, H., Cairns, M., Bojang, K., Coulibaly, S. O., Kayentao, K., Williams, J., Abubakar, I., Akor, F., Mohammed, K., Bationo, R., Dabira, E., Soulama, A., Djimdé, M., Guirou, E., Awine, T., Quaye, S., Njie, F., Ordi, J., Doumbo, O., Hodgson, A. & 9 others, Oduro, A., Meshnick, S., Taylor, S., Magnussen, Pascal, Kuile, F. T., Woukeu, A., Milligan, P., Chandramohan, D. & Greenwood, B., 2015, In: PloS one. 10, 8, 17 p., e0132247.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

    RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA

    Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children

    Tiendrebeogo, R. W., Adu, B., Singh, S. K., Dziegiel, Morten Hanefeld, Nébié, I., Sirima, S. B., Christiansen, M., Dodoo, D. & Theisen, Michael, 2015, In: Open forum in Infectious Diseases. 2, 2, 5 p., ofv044.

    Research output: Contribution to journal › Letter › Research › peer-review

  16. Published

    IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

    Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Rifins, rosetting, and red blood cells

    Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  18. 2014
  19. Published

    A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

    Adjei, G. O., Goka, B. Q., Enweronu-Laryea, C. C., Rodrigues, O. P., Renner, L., Sulley, A. M., Alifrangis, Michael, Khalil, I. & Kurtzhals, Jørgen, 2014, In: Malaria Journal. 13, p. 369

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Fc Gamma Receptor 3B (FCGR3Bc.233C>A-rs5030738) Polymorphism Modifies the Protective Effect of Malaria Specific Antibodies in Ghanaian Children

    Adu, B., Jepsen, M. P. G., Gerds, Thomas Alexander, Kyei-Baafour, E., Christiansen, M., Dodoo, D. & Theisen, Michael, Jan 2014, In: The Journal of Infectious Diseases. 209, 2, p. 285-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Guinea worm (Dracunculiasis) eradication: update on progress and endgame challenges

    Al-Awadi, A. R., Al-Kuhlani, A., Breman, J. G., Doumbo, O., Eberhard, M. L., Guiguemde, R. T., Magnussen, Pascal, Molyneux, D. H. & Nadim, A., 2014, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 108, 5, p. 249-251 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Infections with cardiopulmonary and intestinal helminths and sarcoptic mange in red foxes from two different localities in Denmark

    Al-Sabi, M. M., Halasa, T. & Kapel, Christian, Mar 2014, In: Acta Parasitologica. 59, 1, p. 98-107 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Independent origin of Plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia

    Alifrangis, Michael, Nag, S., Schousboe, M. L., Ishengoma, D., Lusingu, J., Pota, H., Kavishe, R. A., Pearce, R., Ord, R., Lynch, C., Dejene, S., Cox, J., Rwakimari, J., Minja, D. T. R., Lemnge, M. M. & Roper, C., Aug 2014, In: Emerging Infectious Diseases (Print Edition). 20, 8, p. 1280-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site

    Babakhanyan, A., Leke, R. G. F., Salanti, Ali, Bobbili, N., Gwanmesia, P., Leke, R. J. I., Quakyi, I. A., Chen, J. J. & Taylor, D. W., 2014, In: PLOS ONE. 9, 2, p. e88173

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa

    Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes

    Beaudet, J. M., Mansur, L., Joo, E. J., Kamhi, E., Yang, B., Clausen, Thomas Mandel, Salanti, Ali, Zhang, F. & Linhardt, R. J., Feb 2014, In: Glycoconjugate Journal. 31, 2, p. 109-16 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Temporal fluctuations in the sero-prevalence of Taenia solium cysticercosis in pigs in Mbeya Region, Tanzania

    Braae, U. C., Magnussen, Pascal, Lekule, F., Harrison, W. & Johansen, M. V., 2014, In: Parasites & Vectors. 7, 7 p., 574.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study

    Coulibaly, S. O., Kayentao, K., Taylor, S., Guirou, E. A., Khairallah, C., Guindo, N., Djimde, M., Bationo, R., Soulama, A., Dabira, E., Barry, B., Niangaly, M., Diakite, H., Konate, S., Keita, M., Traore, B., Meshnick, S. R., Magnussen, Pascal, Doumbo, O. K. & Ter Kuile, F. O., 2014, In: Malaria Journal. 13, 1, p. 41

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    GLP-1 improves neuropathology after murine cold lesion brain trauma

    DellaValle, B., Hempel, C., Johansen, F. F. & Kurtzhals, Jørgen, Sep 2014, In: Annals of Clinical and Translational Neurology. 1, 9, p. 721-32 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Implementation of minimally invasive and objective humane endpoints in the study of murine Plasmodium infections

    Dellavalle, B., Kirchhoff, J., Maretty, L., Castberg, F. C. & Kurtzhals, Jørgen, 4 Jul 2014, In: Parasitology. 141, 12, p. 1621-1627 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA

    Ditlev, S. B., Florea, R., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Magez, S., Boeuf, P. & Salanti, Ali, 21 Jan 2014, In: PLOS ONE. 9, 1, p. e84981

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Targeted disruption of a ring-infected erythrocyte surface antigen (RESA)-like export protein gene in Plasmodium falciparum confers stable chondroitin 4-sulfate cytoadherence capacity

    Goel, S., Muthusamy, A., Miao, J., Cui, L., Salanti, Ali, Winzeler, E. A. & Gowda, D. C., 5 Dec 2014, In: The Journal of Biological Chemistry. 289, 49, p. 34408-21 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Effects of the vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor SU5416 on in vitro cultures of Plasmodium falciparum

    Hempel, C., Hoyer, N., Staalsø, Trine & Kurtzhals, Jørgen, 2014, In: Malaria Journal. 13, 1, p. 201

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria

    Hempel, C., Hyttel, P. & Kurtzhals, Jørgen, Jul 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 7, p. 1107-10 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity

    Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Systemic and cerebral vascular endothelial growth factor levels increase in murine cerebral malaria along with increased Calpain and caspase activity and can be reduced by erythropoietin treatment

    Hempel, C., Hoyer, N., Kildemoes, A., Jendresen, C. B. & Kurtzhals, Jørgen, 2014, In: Frontiers in Immunology. 5, p. 291

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania

    Kavishe, R. A., Paulo, P., Kaaya, R. D., Kalinga, A., van Zwetselaar, M., Chilongola, J., Roper, C. & Alifrangis, Michael, 9 Jul 2014, In: Malaria Journal. 13, 1, p. 264

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Studies of the aggregation of RNase Sa

    Khasa, H., Kramer, R., Maddux, N., Hamborg, M., Joshi, S. B., Volkin, D. B. & Middaugh, C. R., Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 2, p. 395-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates

    Madkhali, A. M., Alkurbi, M. O., Szestak, T., Bengtsson, A., Patil, P. R., Wu, Y., Alharthi, S., Jensen, Anja Ramstedt, Pleass, R. & Craig, A. G., 2014, In: PLOS ONE. 9, 10, 8 p., e111518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    "Every drug goes to treat its own disease…" - a qualitative study of perceptions and experiences of taking anti-retrovirals concomitantly with anti-malarials among those affected by HIV and malaria in Tanzania

    Mangesho, P. E., Reynolds, J., Lemnge, M., Vestergaard, L. S. & Chandler, C. I. R., 2014, In: Malaria Journal. 13, p. 1-9 491.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Modelling of human transplacental transport as performed in Copenhagen, Denmark

    Mathiesen, Line, Mørck, T. A., Zuri, G., Guerra Andersen, M. H., Pehrson, Caroline, Frederiksen, M., Mose, T., Rytting, E., Poulsen, M. S., Nielsen, J. K. S. & Knudsen, Lisbeth E., Jul 2014, In: Basic & Clinical Pharmacology & Toxicology. 115, 1, p. 93-100 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Introducing rapid diagnostic tests for malaria into drug shops in Uganda: design and implementation of a cluster randomized trial

    Mbonye, A. K., Magnussen, Pascal, Chandler, C. I., Hansen, K. S., Lal, S., Cundill, B., Lynch, C. A. & Clarke, S. E., 2014, In: Trials. 15, 12 p., 303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

    Miura, K., Jongert, E., Deng, B., Zhou, L., Lusingu, J. P., Drakeley, C. J., Fay, M. P., Long, C. A. & Vekemans, J., 2014, In: Malaria Journal. 13, p. 1-9 9 p., 263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Health facility-based data on women receiving sulphadoxine-pyrimethamine during pregnancy in Tanzania: lessons to learn from a cross-sectional survey in Mkuranga and Mufindi districts and other national survey reports

    Mubyazi, G. M., Byskov, J., Magnussen, Pascal, Bygbjerg, Ib Christian, Ijumba, J. N., Marero, M., Mboera, L. E., Molteni, F. & Bloch, P., 2014, In: Reproductive Health. 11, 1, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

    Ocholla, H., Preston, M. D., Mipando, M., Jensen, A. T. R., Campino, S., MacInnis, B., Alcock, D., Terlouw, A., Zongo, I., Oudraogo, J-B., Djimde, A. A., Assefa, S., Doumbo, O. K., Borrmann, S., Nzila, A., Marsh, K., Fairhurst, R. M., Nosten, F., Anderson, T. J. C., Kwiatkowski, D. P. & 3 others, Craig, A., Clark, T. G. & Montgomery, J., 19 Jun 2014, In: The Journal of Infectious Diseases. 210, 12, p. 1991-2000 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

    Sander, Adam F. , Lavstsen, Thomas, Rask, T. S., Lisby, Michael, Salanti, Ali, Fordyce, S. L., Jespersen, Jakob Schmidt, Carter, R., Deitsch, K. W., Theander, Thor Grundtvig, Pedersen, A. G. & Arnot, D. E., 2014, In: Nucleic Acids Research. 42, 4, p. 2270-81 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Prevalence of lymphatic filariasis, malaria and soil transmitted helminthiasis in a community of Bardiya District, western Nepal

    Ranjitkar, S., Alifrangis, Michael, Adhikari, M., Olsen, A., Simonsen, P. E. & Meyrowitsch, Dan Wolf, Nov 2014, In: Southeast Asian Journal of Tropical Medicine and Public Health. 45, 6, p. 1243-1251 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Molecular surveillance for artemisinin resistance in Africa

    Roper, C., Alifrangis, Michael, Ariey, F., Talisuna, A., Menard, D., Mercereau-Puijalon, O. & Ringwald, P., Aug 2014, In: The Lancet Infectious Diseases. 14, 8, p. 668-70 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Co-endemicity of Cysticercosis and Schistosomiasis in Africa - how many people are at risk?

    Saarnak, C., Braae, U. C., Mukaratirwa, S., Magnussen, Pascal & Johansen, M. V., 31 Oct 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  52. Published

    Co-endemicity of Cysticercosis and Schistosomiasis in Africa - how many people are at risk?

    Saarnak, C., Braae, U. C., Magnussen, Pascal, Mukaratirwa, S. & Johansen, M. V., 4 Nov 2014. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

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