VAR2CSA team

  1. 2016
  2. Published

    Influence of intermittent preventive treatment on antibodies to VAR2CSA in pregnant Cameroonian women

    Babakhanyan, A., Tutterrow, Y. L., Bobbili, N., Salanti, Ali, Wey, A., Fogako, J., Leke, R. J., Leke, R. G. F. & Taylor, D. W., Mar 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 3, p. 640-649 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2015
  4. Published

    Ethnomedicinal survey and in vitro anti-plasmodial activity of the palm Borassus aethiopum Mart

    Gruca, M., Yu, W., Amoateng, P., Nielsen, Morten Agertoug, Poulsen, T. B. & Balslev, H., 4 Dec 2015, In: Journal of Ethnopharmacology. 175, p. 356-369 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced

    Rieger, H., Yoshikawa, H. Y., Quadt, K., Nielsen, Morten Agertoug, Sanchez, C. P., Salanti, Ali, Tanaka, M. & Lanzer, M., 8 Jan 2015, In: Blood. 125, 2, p. 383-91 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A novel virus-like particle based vaccine platform displaying the placental malaria antigen VAR2CSA

    Thrane, Susan, Janitzek, C. M., Agerbæk, Mette Ørskov, Ditlev, S. B., dos Santos Marques Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 2015, In: PloS one. 10, 11, 16 p., e0143071.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case-control study

    Babakhanyan, A., Fang, R., Wey, A., Salanti, Ali, Sama, G., Efundem, C., Leke, R. J. I., Chen, J. J., Leke, R. G. F. & Taylor, D. W., 2015, In: Malaria Journal. 14, 10 p., 480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    High-Throughput Testing of Antibody-Dependent Binding Inhibition of Placental Malaria Parasites

    Nielsen, Morten Agertoug & Salanti, Ali, 2015, Malaria Vaccines : Methods and Protocols . Humana Press, Vol. 1325. p. 241-53 13 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

    Doritchamou, J., Sabbagh, A., Jespersen, Jakob Schmidt, Renard, E., Salanti, Ali, Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2015, In: PLOS ONE. 10, 9, 14 p., e0137695.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Protective antibodies against placental malaria and poor outcomes during pregnancy, Benin

    Ndam, N. T., Denoeud-Ndam, L., Doritchamou, J., Viwami, F., Salanti, Ali, Nielsen, Morten Agertoug, Fievet, N., Massougbodji, A., Luty, A. J. F. & Deloron, P., 2015, In: Emerging Infectious Diseases (Print Edition). 21, 5, p. 813-823 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

    Nielsen, M. A., dos Santos Marques Resende, M., de Jongh, W. A., Ditlev, S. B., Mordmüller, B., Houard, S., Ndam, N. T., Agerbæk, M. Ø., Jensen, M. H., Massougbodji, A., Issifou, S., Strøbæk, A., Poulsen, L., Leroy, O., Kremsner, P. G., Chippaux, J-P., Luty, A. J. F., Deloron, P., Theander, T. G., Dyring, C. & 1 others, Salanti, Ali, 2015, In: PloS one. 10, 9, 12 p., e0135406.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2014
  14. Published

    Targeted disruption of a ring-infected erythrocyte surface antigen (RESA)-like export protein gene in Plasmodium falciparum confers stable chondroitin 4-sulfate cytoadherence capacity

    Goel, S., Muthusamy, A., Miao, J., Cui, L., Salanti, Ali, Winzeler, E. A. & Gowda, D. C., 5 Dec 2014, In: The Journal of Biological Chemistry. 289, 49, p. 34408-21 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Modelling of human transplacental transport as performed in Copenhagen, Denmark

    Mathiesen, Line, Mørck, T. A., Zuri, G., Guerra Andersen, M. H., Pehrson, Caroline, Frederiksen, M., Mose, T., Rytting, E., Poulsen, M. S., Nielsen, J. K. S. & Knudsen, Lisbeth E., Jul 2014, In: Basic & Clinical Pharmacology & Toxicology. 115, 1, p. 93-100 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes

    Beaudet, J. M., Mansur, L., Joo, E. J., Kamhi, E., Yang, B., Clausen, Thomas Mandel, Salanti, Ali, Zhang, F. & Linhardt, R. J., Feb 2014, In: Glycoconjugate Journal. 31, 2, p. 109-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA

    Ditlev, S. B., Florea, R., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Magez, S., Boeuf, P. & Salanti, Ali, 21 Jan 2014, In: PLOS ONE. 9, 1, p. e84981

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

    Sander, Adam F. , Lavstsen, Thomas, Rask, T. S., Lisby, Michael, Salanti, Ali, Fordyce, S. L., Jespersen, Jakob Schmidt, Carter, R., Deitsch, K. W., Theander, Thor Grundtvig, Pedersen, A. G. & Arnot, D. E., 2014, In: Nucleic Acids Research. 42, 4, p. 2270-81 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site

    Babakhanyan, A., Leke, R. G. F., Salanti, Ali, Bobbili, N., Gwanmesia, P., Leke, R. J. I., Quakyi, I. A., Chen, J. J. & Taylor, D. W., 2014, In: PLOS ONE. 9, 2, p. e88173

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2013
  21. Published

    Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface

    Tibúrcio, M., Silvestrini, F., Bertuccini, L., Sander, Adam F. , Turner, Louise, Lavstsen, Thomas & Alano, P., 1 Nov 2013, In: Cellular Microbiology Online. 15, 4, p. 647-659

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity

    Tetteh, K. K. A., Osier, F. H. A., Salanti, Ali, Kamuyu, G., Drought, L., Failly, M., Martin, C., Marsh, K. & Conway, D. J., Oct 2013, In: Infection and Immunity. 81, 10, p. 3835-42 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA

    Doritchamou, J., Bigey, P., Nielsen, Morten Agertoug, Gnidehou, S., Ezinmegnon, S., Burgain, A., Massougbodji, A., Deloron, P., Salanti, Ali & Ndam, N. T., 23 Sep 2013, In: Vaccine. 31, 41, p. 4516-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Severe malaria is associated with parasite binding to endothelial protein C receptor

    Turner, Louise, Lavstsen, Thomas, Berger, S. S., Wang, Christian William, Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, Jakob Schmidt, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, Thor Grundtvig, 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin

    Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Malaria and Fetal Growth Alterations in the 3(rd) Trimester of Pregnancy: A Longitudinal Ultrasound Study

    Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, Caroline, Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Nielsen, B. B., Lusingu, J. & Theander, Thor Grundtvig, 2013, In: P L o S One. 8, 1, p. e53794

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria

    Fried, M., Avril, M., Chaturvedi, R., Fernandez, P., Lograsso, J., Narum, D., Nielsen, Morten Agertoug, Oleinikov, A. V., Resende, M., Salanti, Ali, Saveria, T., Williamson, K., Dicko, A., Scherf, A., Smith, J. D., Theander, Thor Grundtvig & Duffy, P. E., 2013, In: Infect Immun. 81, 2, p. 487-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    New horizons for lipoprotein receptors: communication by β-propellers

    Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review