VAR2CSA team

  1. 2020
  2. Published

    An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer

    Toledo, A. G., Pihl, J., Spliid, C. B., Persson, A., Nilsson, J., Pereira, M. A., Gustavsson, Tobias, Choudhary, Swati, Zarni Oo, H., Black, P. C., Daugaard, M., Esko, J. D., Larson, G., Salanti, Ali & Clausen, Thomas Mandel, 2020, In: Glycobiology. 30, 12, p. 989-1002 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Antibodies to full-length and the DBL5 domain of VAR2CSA in pregnant women after long-term implementation of intermittent preventive treatment in Etoudi, Cameroon

    Djontu, J. C., Lloyd, Y. M., Megnekou, R., Seumko'o, R. M. N., Salanti, Ali, Taylor, D. W. & Leke, R. G. F., 2020, In: PLoS ONE. 15, 8, 13 p., e0237671.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

    Harmsen, C., Turner, Louise, Thrane, Susan, Sander, Adam F. , Theander, Thor Grundtvig & Lavstsen, Thomas, 2020, In: Malaria Journal. 19, 1, 11 p., 132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Optimization of rVAR2-based isolation of cancer cells in blood for building a robust assay for clinical detection of circulating tumor cells

    Sand, Nicolai Tue, Petersen, T. B., Bang-Christensen, S. R., Ahrens, T. D., Løppke, Caroline Bang, Jørgensen, A. M., Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali & Agerbæk, Mette Ørskov, 2020, In: International Journal of Molecular Sciences . 21, 7, 2401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Premetastatic niches, exosomes and circulating tumor cells: Early mechanisms of tumor dissemination and the relation to surgery

    Raskov, H., Orhan, Adile, Salanti, Ali & Gögenur, Ismail, 2020, In: International Journal of Cancer. 146, 12, p. 3244-3255

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

    Clausen, T. M., Sandoval, D. R., Spliid, C. B., Pihl, J., Perrett, H. R., Painter, C. D., Narayanan, A., Majowicz, S. A., Kwong, E. M., McVicar, R. N., Thacker, B. E., Glass, C. A., Yang, Z., Torres, J. L., Golden, G. J., Bartels, P. L., Porell, R. N., Garretson, A. F., Laubach, L., Feldman, J. & 16 others, Yin, X., Pu, Y., Hauser, B. M., Caradonna, T. M., Kellman, B. P., Martino, C., Gordts, P. L. S. M., Chanda, S. K., Schmidt, A. G., Godula, K., Leibel, S. L., Jose, J., Corbett, K. D., Ward, A. B., Carlin, A. F. & Esko, J. D., 2020, In: Cell. 183, 4, p. 1043-1057.e15

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

    Ahrens, T. D., Bang-Christensen, S. R., Jørgensen, A. M., Løppke, Caroline Bang, Spliid, C. B., Sand, Nicolai Tue, Clausen, Thomas Mandel, Salanti, Ali & Agerbæk, Mette Ørskov, 2020, In: Frontiers in Cell and Developmental Biology. 8, 27 p., 749.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Virus-like particles displaying major HDM allergen Der p 2 for prophylactic allergen immunotherapy

    Soongrung, T., Mongkorntanyatip, K., Peepim, T., Jitthamstaporn, S., Pitakpolrat, P., Kaewamatawong, T., Janitzek, C. M., Thrane, Susan, Sander, Adam F. & Jacquet, A., 2020, In: Allergy: European Journal of Allergy and Clinical Immunology. 75, 5, p. 1232-1236

    Research output: Contribution to journalLetterResearchpeer-review

  10. 2019
  11. Published

    A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine

    Janitzek, C. M., Peabody, J., Thrane, Susan, H R Carlsen, P., Theander, Thor Grundtvig, Salanti, Ali, Chackerian, B., Nielsen, Morten Agertoug & Sander, Adam F. , 2019, In: Scientific Reports. 9, 1, 10 p., 5260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity between Plasmodium vivax PvDBP and Plasmodium falciparum VAR2CSA

    Mitran, C. J., Mena, A., Gnidehou, S., Banman, S., Arango, E., Lima, B. A. S., Lugo, H., Ganesan, A., Salanti, Ali, Mbonye, A. K., Ntumngia, F., Barakat, K., Adams, J. H., Kano, F. S., Carvalho, L. H., Maestre, A. E., Good, M. F. & Yanow, S. K., 2019, In: mBio. 10, 5, 17 p., e02343-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

    Bang-Christensen, S. R., Pedersen, R. S., Pereira, M. A., Clausen, T. M., Løppke, C., Sand, N. T., Ahrens, T. D., Jørgensen, A. M., Lim, Y. C., Goksøyr, L., Choudhary, S., Gustavsson, T., Dagil, R., Daugaard, M., Sander, A. F., Torp, M. H., Søgaard, M., Theander, T. G., Østrup, O., Lassen, U. & 3 others, Hamerlik, P., Salanti, Ali & Agerbæk, Mette Ørskov, 2019, In: Cells. 8, 9, 21 p., 998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Cross-species immune recognition between Plasmodium vivax Duffy binding protein antibodies and the Plasmodium falciparum surface antigen VAR2CSA

    Gnidehou, S., Mitran, C. J., Arango, E., Banman, S., Mena, A., Medawar, E., Lima, B. A. S., Doritchamou, J., Rajwani, J., Jin, A., Gavina, K., Ntumngia, F., Duffy, P., Narum, D., Ndam, N. T., Nielsen, M. A., Salanti, A., Kano, F. S., Carvalho, L. H., Adams, J. H. & 3 others, Maestre, A., Good, M. F. & Yanow, S. K., 2019, In: The Journal of Infectious Diseases. 219, 1, p. 110-120 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Fighting cancer using an oncofetal glycosaminoglycan-binding protein from malaria parasites

    Agerbæk, Mette Ørskov, Bang-Christensen, S. & Salanti, Ali, 2019, In: Trends in Parasitology. 35, 3, p. 178-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

    Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, Reed, S. G., Leroy, O., Luty, A. J. F., Theander, Thor Grundtvig, Kremsner, P. G., Salanti, Ali & Nielsen, Morten Agertoug, 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties

    Dagil, Robert, Ball, N. J., Ogrodowicz, R. W., Hobor, F., Purkiss, A. G., Kelly, G., Martin, S. R., Taylor, I. A. & Ramos, A., 2019, In: Nucleic Acids Research. 47, 8, p. 4334-4348 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

    Singh, S. K., Thrane, Susan, Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G., van de Vegte-Bolmer, M. G., Nielsen, Morten Agertoug, Salanti, Ali, Sander, Adam F. , Sauerwein, R. W., Jore, M. M. & Theisen, Michael, 2019, In: Frontiers in Immunology. 10, 1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2018
  20. Published

    Clinical outcomes of submicroscopic infections and correlates of protection of VAR2CSA antibodies in a longitudinal study of pregnant women in Colombia

    Gavina, K., Gnidehou, S., Arango, E., Hamel-Martineau, C., Mitran, C., Agudelo, O., Lopez, C., Karidio, A., Banman, S., Carmona-Fonseca, J., Salanti, Ali, Tuikue Ndam, N., Hawkes, M., Maestre, A. & Yanow, S. K., Apr 2018, In: Infection and Immunity. 86, 4, e00797-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Association of antibodies to VAR2CSA and merozoite antigens with pregnancy outcomes in women living in Yaoundé, Cameroon

    Lloyd, Y. M., Fang, R., Bobbili, N., Vanda, K., Ngati, E., Sanchez-Quintero, M. J., Salanti, Ali, Chen, J. J., Rose, R. G. & Taylor, D. W., 2018, In: Infection and Immunity. 86, 9, e00166-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Debugging diversity – a pan-continental exploration of the potential of terrestrial blood-feeding leeches as a vertebrate monitoring tool

    Schnell, I. B., Bohmann, K., Schultze, S. E., Richter, S. R., Murray, D. C., Sinding, M. H. S., Bass, D., Cadle, J. E., Campbell, M. J., Dolch, R., Edwards, D. P., Gray, T. N. E., Hansen, T., Hoa, A. N. Q., Noer, C. L., Heise-Pavlov, S., Sander Pedersen, A. F., Ramamonjisoa, J. C., Siddall, M. E., Tilker, A. & 7 others, Traeholt, C., Wilkinson, N., Woodcock, P., Yu, D. W., Bertelsen, Mads Frost, Bunce, M. & Gilbert, M Thomas P, 2018, In: Molecular Ecology Resources. 18, 6, p. 1282-1298 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Persistent Plasmodium falciparum Infection in Women With an Intent to Become Pregnant as a Risk Factor for Pregnancy-associated Malaria

    Tuikue Ndam, N., Tornyigah, B., Dossou, A. Y., Escriou, G., Nielsen, Morten Agertoug, Salanti, Ali, Issifou, S., Massougbodji, A., Chippaux, J. P. & Deloron, P., 2018, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67, 12, p. 1890-1896 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

    Agerbæk, Mette Ørskov, Bang-Christensen, S. R., Yang, M., Clausen, Thomas Mandel, Pereira, M. A., Sharma, S., Ditlev, S. B., Nielsen, Morten Agertoug, Choudhary, Swati, Gustavsson, Tobias, Sorensen, P. H., Meyer, T., Propper, D., Shamash, J., Theander, Thor Grundtvig, Aicher, A., Daugaard, M., Heeschen, C. & Salanti, Ali, 2018, In: Nature Communications. 9, 1, 13 p., 3279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Virus-like antigen display for cancer vaccine development, what is the potential?

    Sander, Adam F. & Lollini, P., 2018, In: Expert Review of Vaccines. 17, 4, p. 285-288 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  26. Published

    Virus-like particle display of HER2 induces potent anti-cancer responses

    Palladini, A., Thrane, Susan, Janitzek, C. M., Pihl, J., Clemmensen, S. B., de Jongh, W. A., Clausen, Thomas Mandel, Nicoletti, G., Landuzzi, L., Penichet, M. L., Balboni, T., Ianzano, M. L., Giusti, V., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Lollini, P., Nanni, P. & Sander, Adam F. , 2018, In: OncoImmunology. 7, 3, 12 p., e1408749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2017
  28. Published

    Plasmodium falciparum infection early in pregnancy has profound consequences for fetal growth

    Schmiegelow, Christentze, Matondo, S., Minja, D. T. R., Resende, M., Pehrson, Caroline, Nielsen, B. B., Olomi, R., Nielsen, Morten Agertoug, Deloron, P., Salanti, Ali, Lusingu, J. & Theander, Thor Grundtvig, 19 Dec 2017, In: The Journal of Infectious Diseases. 216, 12, p. 1601-1610 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Rainbow trout (Oncorhynchus mykiss) immune response towards a recombinant vaccine targeting the parasitic ciliate Ichthyophthirius multifiliis

    Jørgensen, Louise von Gersdorff, Kania, Per, Rasmussen, K. J., Mattsson, A., Schmidt, J. G., Al-Jubury, Azmi, Sander, Adam F. , Salanti, Ali & Buchmann, Kurt, Dec 2017, In: Journal of Fish Diseases. 40, 12, p. 1815–1821

    Research output: Contribution to journalJournal articleResearchpeer-review