VAR2CSA team

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  1. 2021
  2. Published

    Head-to-head comparison of modular vaccines developed using different capsid virus-like particle backbones and antigen conjugation systems

    Fredsgaard, L., Goksøyr, L., Thrane, Susan, Aves, Kara-Lee, Theander, Thor Grundtvig & Sander, Adam F. , Jun 2021, In: Vaccines. 9, 6, 11 p., 539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Plasmodium falciparum VAR2CSA-specific IgG subclass responses reflect protection against low birth weight and pregnancy-associated malaria

    Tornyigah, B., d'Almeida, T., Escriou, G., Viwami, F., Fievet, N., Luty, A. J. F., Massougbodji, A., Nielsen, Morten Agertoug, Deloron, P. & Tuikue Ndam, N., 2021, In: Frontiers in Immunology. 12, 8 p., 610305.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

    Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Antibody mediated activation of natural killer cells in malaria exposed pregnant women

    Damelang, T., Aitken, E. H., Hasang, W., Lopez, E., Killian, M., Unger, H. W., Salanti, Ali, Shub, A., McCarthy, E., Kedzierska, K., Lappas, M., Kent, S. J., Rogerson, S. J. & Chung, A. W., 2021, In: Scientific Reports. 11, 4130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens

    Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Goksøyr, L., Olsen, Rebecca Wendelboe, Fanalista, Margherita, Augestad, Elias Honerød, Thrane, Susan, Pihl, A. F., Gottwein, Judith Margarete, Sander, Adam F. & Bukh, Jens, 2021, In: PLoS ONE. 16, e0255336.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Beware, commercial chondroitinases vary in activity and substrate specificity

    Spliid, C. B., Toledo, A. G., Salanti, Ali, Esko, J. D. & Clausen, Thomas Mandel, 2021, In: Glycobiology. 31, 2, p. 103-115 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, Theisen, Michael, Singh, S. K., Garcia-Senosiain, A., Van Oosten, L., Pijlman, G., Hierzberger, B., Domeyer, T., Nalewajek, B. W., Strøbæk, A., Skrzypczak, M., Andersson, L. F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, T. J., Iversen, Kasper, Harritshøj, L. H., Mordmüller, B., Ullum, H., Reinert, L. S., de Jongh, W. A., Kikkert, M., Paludan, S. R., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali & Sander, Adam F. , 2021, In: Nature Communications. 12, 1, p. 324

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Y., Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Detection of VAR2CSA‐captured colorectal cancer cells from blood samples by real‐time reverse transcription PCR

    Bang‐christensen, S. R., Katerov, V., Jørgensen, Amalie Mundt, Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali, Allawi, H. T. & Agerbæk, Mette Ørskov, 2021, In: Cancers. 13, 23, 5881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

    Aitken, E. H., Damelang, T., Ortega-Pajares, A., Alemu, A., Hasang, W., Dini, S., Unger, H. W., Ome-Kaius, M., Nielsen, Morten Agertoug, Salanti, Ali, Smith, J., Kent, S., Hogarth, P. M., Wines, B. D., Simpson, J. A., Chung, A. & Rogerson, S. J., 2021, In: eLife. 10, e65776.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Development of a bispecific immune engager using a recombinant malaria protein

    Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates

    Karlsson, R., Chopra, P., Joshi, A., Yang, Zhang, Vakhrushev, Sergey, Clausen, Thomas Mandel, Painter, C. D., Szekeres, G. P., Chen, Yen-Hsi, Sandoval, D. R., Hansen, Lars, Esko, J. D., Pagel, K., Dyer, D. P., Turnbull, Jeremy Ewan, Clausen, Henrik, Boons, G. J. & Miller, Rebecca Louise, 2021, In: Science Advances. 7, 52, eabl6026.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate

    Weiss, R. J., Spahn, P. N., Chiang, A. W. T., Liu, Q., Li, J., Hamill, K. M., Rother, S., Clausen, Thomas Mandel, Hoeksema, M. A., Timm, B. M., Godula, K., Glass, C. K., Tor, Y., Gordts, P. L. S. M., Lewis, N. E. & Esko, J. D., 2021, In: Nature Chemical Biology. 17, p. 684–692

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma

    Nieto-Fontarigo, J. J., Tillgren, S., Cerps, S., Sverrild, A., Hvidtfeldt, M., Ramu, S., Menzel, Mandy, Sander, Adam F. , Porsbjerg, Celeste Michala & Uller, L., 2021, In: Frontiers in Immunology. 12, 743890.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Natural Killer Cells in Cancer and Cancer Immunotherapy

    Raskov, H., Orhan, Adile, Salanti, Ali, Gaggar, S. & Gögenur, Ismail, 2021, In: Cancer Letters. 520, p. 233-242 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Oncofetal chondroitin sulfate is a highly expressed therapeutic target in non-small cell lung cancer

    Oo, H. Z., Lohinai, Z., Khazamipour, N., Lo, J., Kumar, G., Pihl, J., Adomat, H., Nabavi, N., Behmanesh, H., Zhai, B., Dagil, R., Choudhary, S., Gustavsson, T., Clausen, T. M., Esko, J. D., Allen, J. W., Thompson, M. A., Tran, N. L., Moldvay, J., Dome, B. & 4 others, Salanti, Ali, Al-Nakouzi, N., Weiss, G. J. & Daugaard, M., 2021, In: Cancers. 13, 17, 16 p., 4489.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Progress and insights toward an effective placental malaria vaccine

    Gamain, B., Chêne, A., Viebig, N. K., Tuikue Ndam, N. & Nielsen, Morten Agertoug, 2021, In: Frontiers in Immunology. 12, 634508.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Site-specific O-glycosylation analysis of SARS-CoV-2 spike protein produced in insect and human cells

    Bagdonaite, Ieva , Thompson, A. J., Wang, X., Søgaard, M., Fougeroux, Cyrielle Elyette, Frank, M., Diedrich, J. K., Yates, J. R., Salanti, Ali, Vakhrushev, Sergey, Paulson, J. C. & Wandall, Hans H., 2021, In: Viruses. 13, 4, 551.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Structure-guided design of a synthetic mimic of an endothelial protein C receptor-binding PfEMP1 protein

    Barber, N. M., Lau, C. K. Y., Turner, Louise, Watson, G., Thrane, Susan, Lusingu, J. P. A., Lavstsen, Thomas & Higgins, M. K., 2021, In: mSphere. 6, 1, 14 p., e01081-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The development, fine specificity, and importance of high-avidity antibodies to VAR2CSA in pregnant Cameroonian women living in Yaoundé, an urban city

    Vanda, K., Bobbili, N., Matsunaga, M., Chen, J. J., Salanti, Ali, Leke, R. F. G. & Taylor, D. W., 2021, In: Frontiers in Immunology. 12, p. 610108

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The immunogenicity of capsid-like particle vaccines in combination with different adjuvants using different routes of administration

    Janitzek, C. M., Carlsen, P. H. R., Thrane, Susan, Khanna, V. M., Jakob, V., Barnier-Quer, C., Collin, N., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2021, In: Vaccines. 9, 2, 131.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility

    Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, Tobias, Choudhary, Swati, Saldanha, A. L., Vogelsang, R. P., Gögenur, Ismail, Theander, Thor Grundtvig, Leach, F. E., Amster, I. J., Esko, J. D., Salanti, Ali & Clausen, Thomas Mandel, 2021, In: The Journal of Biological Chemistry. 297, 6, 15 p., 101391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2020
  25. Published

    A simple method for detecting oncofetal chondroitin sulfate glycosaminoglycans in bladder cancer urine

    Clausen, Thomas Mandel, Kumar, G., Ibsen, E. K., Ørum-Madsen, M. S., Hurtado-Coll, A., Gustavsson, Tobias, Agerbæk, Mette Ørskov, Gatto, F., Todenhöfer, T., Basso, U., Knowles, M. A., Sanchez-Carbayo, M., Salanti, Ali, Black, P. C. & Daugaard, M., 2020, In: Cell Death Discovery. 6, 65.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A vaccine displaying a trimeric influenza-A HA stem protein on capsid-like particles elicits potent and long-lasting protection in mice

    Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida Elin Maria, Janitzek, C. M., Han, J., Yang, Y. R., Ward, A. B., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Thomsen, Allan Randrup, Christensen, Jan Pravsgaard & Sander, Adam F. , 2020, In: Vaccines. 8, 3, 389.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Advantages and Prospects of Tag/Catcher Mediated Antigen Display on Capsid-Like Particle-Based Vaccines

    Aves, Kara-Lee, Goksøyr, L. & Sander, Adam F. , 2020, In: Viruses. 12, 2, 185.

    Research output: Contribution to journal › Review › Research › peer-review

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