VAR2CSA team

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  1. 2023
  2. Published

    Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

    Doritchamou, J., Nielsen, M. A., Chêne, A., Viebig, N. K., Lambert, L. E., Sander, A. F., Semblat, J. P., Hundt, S., Orr-Gonzalez, S., Janitzek, C. M., Spiegel, A. J., Clemmensen, S. B., Thomas, M. L., Nason, M. C., Snow-Smith, M., Barnafo, E. K., Shiloach, J., Chen, B. B., Nadakal, S., Highsmith, K. & 15 others, Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K. M., Scaria, P. V., Anderson, C., Narum, D. L., Salanti, Ali, Fried, M., Theander, Thor Grundtvig, Gamain, B. & Duffy, P. E., 2023, In: Lab Animal. 52, 12, p. 315-323

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A Virus-like Particle-Based F4 Enterotoxigenic Escherichia coli Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows

    Aves, Kara-Lee, Guerra, Priscila Regina, Fresno, A. H., Saraiva, M. M. S., Cox, E., Bækbo, P. J., Nielsen, Morten Agertoug, Sander, Adam F. & Olsen, John Elmerdahl, 2023, In: Pathogens. 12, 12, 19 p., 1388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A cVLP-based vaccine displaying full-length PCSK9 elicits a higher reduction in plasma PCSK9 than similar peptide-based cVLP vaccines

    Goksøyr, L., Skrzypczak, M., Sampson, M., Nielsen, Morten Agertoug, Salanti, Ali, Theander, Thor Grundtvig, Remaley, A. T., Jongh, W. A. D. & Sander, Adam F. , 2023, In: Vaccines. 11, 1, 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

    Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Characterization of SARS-CoV-2 humoral immune response in a subject with unique sampling: A case report

    Walker, Melanie Rose, Idorn, M., Bennett, Anja, Søgaard, M., Salanti, Ali, Ditlev, S. B. & Barfod, Lea Klingenberg, 2023, In: Immunity, Inflammation and Disease. 11, 6, e910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines

    Van Coillie, J., Pongracz, T., Šuštić, T., Wang, W., Nouta, J., Le Gars, M., Keijzer, S., Linty, F., Cristianawati, O., Keijser, J. B. D., Visser, R., van Vught, L. A., Slim, M. A., van Mourik, N., Smit, M. J., Sander, A., Schmidt, D. E., Steenhuis, M., Rispens, T., Nielsen, M. A. & 31 others, Mordmüller, B. G., Vlaar, A. P. J., Ellen van der Schoot, C., Roozendaal, R., Wuhrer, M., Vidarsson, G., Appelman, B., van de Beek, D., Bomers, M. K., de Brabander, J., Brouwer, M. C., Buis, D. T. P., Chekrouni, N., van Gils, M. J., de Jong, M. D., Lavell, A. H. A., Olie, S. E., Peters, E. J. G., Reijnders, T. D. Y., Schinkel, M., Schuurman, A. R., Sikkens, J. J., Smulders, Y. M., Wiersinga, J. W., Spinello, A., Bassoli, C., Bestetti, G., Corbellino, M., Salanti, Ali, Theander, Thor Grundtvig & in collaboration with the UMC COVID-19 S3/HCW study group, I. C. W. T. U. C. S. S. G., 2023, In: iScience. 26, 9, p. 1-15 107619.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

    Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    High immunogenicity of virus-like particles (VLPs) decorated with Aeromonas salmonicida VapA antigen in rainbow trout

    Yang, J. I., Sepúlveda, D., Vardia, I., Skov, J., Goksøyr, L., Sander, Adam F. & Lorenzen, N., 2023, In: Frontiers in Immunology. 14, 1139206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching

    Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, Saar, Daniel, Blæsild, H., Stahlhut, M., Andersen, K. V., Dagil, Robert, Vestergaard, Bente, Ryberg, Marie L. & Kragelund, Birthe Brandt, 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Malaria biomimetic for tumor targeted drug delivery

    Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2022
  13. Published

    A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects Rhesus macaques

    Volkmann, A., Koopman, G., Mooij, P., Verschoor, E. J., Verstrepen, B. E., Bogers, W. M. J. M., Idorn, M., Paludan, S. R., Vang, S., Nielsen, Morten Agertoug, Sander, Adam F. , Schmittwolf, C., Hochrein, H. & Chaplin, P., 2022, In: Frontiers in Immunology. 13, p. 857440

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    An S1-Nanoparticle Vaccine Protects against SARS-CoV-2 Challenge in K18-hACE2 Mice

    van Oosten, L., Yan, K., Rawle, D. J., Le, T. T., Altenburg, J. J., Fougeroux, Cyrielle Elyette, Goksøyr, L., de Jongh, W. A., Nielsen, Morten Agertoug, Sander, Adam F. , Pijlman, G. P. & Suhrbier, A., 2022, In: Journal of Virology. 96, 14, 00844-22.

    Research output: Contribution to journal › Letter › Research › peer-review

  15. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Development of a synthetic nanoparticle vaccine presenting the HIV-1 envelope glycoprotein

    Ximba, P., Chapman, R., Meyers, A., Margolin, E., van Diepen, M. T., Sander, Adam F. , Woodward, J., Moore, P. L., Williamson, A. L. & Rybicki, E. P., 2022, In: Nanotechnology. 33, 48, 16 p., 485102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature

    Aves, Kara-Lee, Janitzek, C. M., Fougeroux, Cyrielle Elyette, Theander, Thor Grundtvig & Sander, Adam F. , 2022, In: Pharmaceutics. 14, 6, 1301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells

    Wang, Chris Kedong, Nelepcu, I., Hui, D., Oo, H. Z., Truong, S., Zhao, S., Tahiry, Z., Esfandnia, S., Ghaidi, F., Adomat, H., Dagil, Robert, Gustavsson, Tobias, Choudhary, Swati, Salanti, Ali, Sorensen, P. H., Al Nakouzi, N. & Daugaard, M., 2022, In: Scientific Reports. 12, 3075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Noninvasive detection of any-stage cancer using free glycosaminoglycans

    Bratulic, S., Limeta, A., Dabestani, S., Birgisson, H., Enblad, G., Stålberg, K., Hesselager, G., Häggman, M., Höglund, M., Simonson, O. E., Stålberg, P., Lindman, H., Bång-Rudenstam, A., Ekstrand, M., Kumar, G., Cavarretta, I., Alfano, M., Pellegrino, F., Mandel-Clausen, T., Salanti, A. & 16 others, Maccari, F., Galeotti, F., Volpi, N., Daugaard, M., Belting, M., Lundstam, S., Stierner, U., Nyman, J., Bergman, B., Edqvist, P., Levin, M., Salonia, A., Kjölhede, H., Jonasch, E., Nielsen, J. & Gatto, F., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 50, p. e2115328119

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1β for Treatment of Allergic Contact Dermatitis

    Goksøyr, L., Funch, Anders Boutrup, Okholm, A. K., Theander, Thor Grundtvig, de Jongh, W. A., Bonefeld, Charlotte Menne & Sander, Adam F. , 2022, In: Vaccines. 10, 5, 828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer

    Al Nakouzi, N., Wang, C. K., Oo, H. Z., Nelepcu, I., Lallous, N., Spliid, C. B., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Clausen, T. M., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A. & 6 others, Fazli, L., Esko, J. D., Salanti, Ali, Nelson, P. S., Gleave, M. & Daugaard, M., 2022, In: Nature Communications. 13, 4760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    SARS-CoV-2 RBD-specific antibodies induced early in the pandemic by natural infection and vaccination display cross-variant binding and inhibition

    Walker, Melanie Rose, Podlekareva, D., Johnsen, Stine, Leerhøy, B., Fougeroux, Cyrielle Elyette, Søgaard, M., Salanti, Ali, Ditlev, S. B. & Barfod, Lea Klingenberg, 2022, In: Viruses. 14, 9, 14 p., 1861.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Seroprevalence of SARS-CoV-2 antibodies among children and adolescents recruited in a malariometric survey in north-eastern Tanzania July 2021

    Lyimo, E., Fougeroux, Cyrielle Elyette, Malabeja, A., Mbwana, J., Hayuma, P. M., Liheluka, E., Turner, Louise, Gesase, S., Lavstsen, Thomas, Lusingu, J. P. A., Minja, D. T. R. & Wang, Christian William, 2022, In: BMC Infectious Diseases. 22, 846.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization

    Farzadfard, A., Pedersen, J. N., Meisl, G., Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, Morten Agertoug, Sander, Adam F. , Knowles, T. P. J., Pedersen, J. S. & Otzen, D. E., 2022, In: Communications Biology . 5, 1, 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers

    Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Sørensen, Andreas Holst Holmegaard, Jørgensen, T., Clemmensen, S., Soroka, V., Thrane, Susan, Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali, Bukh, Jens & Sander, Adam F. , 2022, In: npj Vaccines. 7, 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Virus-like particles displaying recombinant Der p 1 allergen to optimize IgG blocking antibody response

    Jitthamstaporn, S., Sander, Adam F. & Jacquet, A., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 2, p. 664-667

    Research output: Contribution to journal › Letter › Research › peer-review

  27. 2021
  28. Published

    Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants

    van Oosten, L., Altenburg, J. J., Fougeroux, C., Geertsema, C., van den End, F., Evers, W. A. C., Westphal, A. H., Lindhoud, S., van den Berg, W., Swarts, D. C., Deurhof, L., Suhrbier, A., Le, T. T., Torres Morales, S., Myeni, S. K., Kikkert, M., Sander, A. F., de Jongh, W. A., Dagil, R., Nielsen, M. A. & 9 others, Salanti, Ali, Søgaard, M., Keijzer, T. M. P., Weijers, D., Eppink, M. H. M., Wijffels, R. H., van Oers, M. M., Martens, D. E. & Pijlman, G. P., 26 Oct 2021, In: mBio. 12, 5, e0181321.

    Research output: Contribution to journal › Journal article › Research › peer-review

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