VAR2CSA team

  1. 2007
  2. Published

    Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

    Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

    Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka

    Schousboe, M. L., Rajakaruna, R. S., Salanti, Ali, Hapuarachchi, H. C., Galappaththy, G. N. L., Bygbjerg, Ib Christian, Amerasinghe, P. H., Konradsen, Flemming & Alifrangis, Michael, 2007, In: Malaria Journal. 6, p. 28

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria

    Hviid, Lars & Salanti, Ali, 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases

    Carey, J., Brynda, J., Wolfová, J., Grandori, R., Gustavsson, Tobias, Ettrich, R. & Smatanová, I. K., Oct 2007, In: Protein Science. 16, 10, p. 2301-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2008
  9. Published

    Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression

    Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

    Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

    Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum

    Guitard, J., Cottrell, G., Magnouha, N. M., Salanti, Ali, Li, T., Sow, S., Deloron, P. & Tuikue Ndam, N., 2008, In: Malaria Journal. 7, p. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA

    Avril, M., Kulasekara, B. R., Gose, S. O., Rowe, C., Dahlbäck, M., Duffy, P. E., Fried, M., Salanti, Ali, Misher, L., Narum, D. L. & Smith, J. D., 2008, In: Infection and Immunity. 76, 4, p. 1791-800 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA

    Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA

    Andersen, P., Nielsen, Morten Agertoug, Resende, M., Rask, T. S., Dahlbäck, M., Theander, Thor Grundtvig, Lund, O. & Salanti, Ali, 2008, In: PLoS Pathogens. 4, 2, p. e42

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

    Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Direct and mediated electron transfer between intact succinate:quinone oxidoreductase from Bacillus subtilis and a surface modified gold electrode reveals redox state-dependent conformational changes

    Christenson, A., Gustavsson, Tobias, Gorton, L. & Hägerhäll, C., Sep 2008, In: B B A - Reviews on Cancer. 1777, 9, p. 1203-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2009
  19. Published

    An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

    Amulic, B., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug & Deitsch, K. W., 2009, In: PLoS Pathogens. 5, 1, p. e1000256

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites

    Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA

    Nielsen, Morten Agertoug, Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, Thor Grundtvig & Salanti, Ali, 2009, In: Infection and Immunity. 77, 6, p. 2482-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

    Sander, Adam F. , Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Magistrado, P., Lusingu, J., Ndam, N. T. & Arnot, D. E., 2009, In: PLoS ONE. 4, 8, p. e6667

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

    Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

    Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

    Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Electrical wiring of live, metabolically enhanced Bacillus subtilis cells with flexible osmium-redox polymers

    Coman, V., Gustavsson, Tobias, Finkelsteinas, A., von Wachenfeldt, C., Hägerhäll, C. & Gorton, L., 11 Nov 2009, In: Journal of the American Chemical Society. 131, 44, p. 16171-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2010
  28. Published

    Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains?

    Dahlbäck, M., Nielsen, Morten Agertoug & Salanti, Ali, 2010, In: Trends in Parasitology. 26, 5, p. 230-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

    Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Dual stage synthesis and crucial role of cytoadherence-linked asexual gene 9 in the surface expression of malaria parasite var proteins

    Goel, S., Valiyaveettil, M., Achur, R. N., Goyal, A., Mattei, D., Salanti, Ali, Trenholme, K. R., Gardiner, D. L. & Gowda, D. C., 2010, In: Proceedings of the National Academy of Science of the United States of America. 107, 38, p. 16643-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies

    Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    IgM, FcµRs, and malarial immune evasion

    Czajkowsky, D. M., Salanti, Ali, Ditlev, S. B., Shao, Z., Ghumra, A., Rowe, J. A. & Pleass, R. J., 2010, In: Journal of Immunology. 184, 9, p. 4597-603 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Macrogeographical variability in the great call of Hylobates agilis: assessing the applicability of vocal analysis in studies of fine-scale taxonomy of gibbons

    Heller, Rasmus, Sander, Adam F. , Wang, Christian William, Usman, F. & Dabelsteen, Torben, 2010, In: American Journal of Primatology. 72, 2, p. 142-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies

    Salanti, Ali, Resende, M., Ditlev, S. B., Pinto, V. V., Dahlbäck, M., Andersen, G., Manczak, T., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2010, In: Malaria Journal. 9, 1, p. 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

    Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Nodulaer hyperplasi af Bartholins kirtel

    Hjortø, S. P., Pehrson, Caroline & Gernow, A., 22 Mar 2010, In: Ugeskrift for Laeger. 172, 12, p. 969-70 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Photolabile ubiquinone analogues for identification and characterization of quinone binding sites in proteins

    Pei, Z., Gustavsson, Tobias, Roth, R., Frejd, T. & Hägerhäll, C., 15 May 2010, In: Bioorganic & Medicinal Chemistry. 18, 10, p. 3457-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A cytochrome c fusion protein domain for convenient detection, quantification, and enhanced production of membrane proteins in Escherichia coli--expression and characterization of cytochrome-tagged Complex I subunits

    Gustavsson, Tobias, Trane, M., Moparthi, V. K., Miklovyte, E., Moparthi, L., Górecki, K., Leiding, T., Arsköld, S. P. & Hägerhäll, C., Aug 2010, In: Protein Science. 19, 8, p. 1445-60 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2011
  40. Published

    Evaluation and impact of cardiotocography training programmes: a systematic review

    Pehrson, Caroline, Sorensen, Jette Led & Amer-Wåhlin, I., 2011, In: British Journal of Obstetrics & Gynaecology. Supplement. 118, 8, p. 926-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

    Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

    Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

    Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The NTS-DBL2X region of VAR2CSA Induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A

    Bigey, P., Gnidehou, S., Doritchamou, J., Quiviger, M., Viwami, F., Couturier, A., Salanti, Ali, Nielsen, Morten Agertoug, Scherman, D., Deloron, P. & Tuikue Ndam, N., 2011, In: Journal of Infectious Diseases. 204, 7, p. 1125-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains

    Dahlbäck, M., Jørgensen, L. M., Nielsen, Morten Agertoug, Clausen, T. M., Ditlev, S. B., Resende, M., Pinto, V. V., Arnot, D. E., Theander, Thor Grundtvig & Salanti, Ali, 2011, In: The Journal of Biological Chemistry. 286, 18, p. 15908-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA

    Pinto, V. V., Ditlev, S. B., Jensen, K. E., Resende, M., Dahlbäck, M., Andersen, G., Andersen, P., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 1 Jan 2011, In: P L o S One. 6, 3, p. e17942

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2012
  48. Published

    Biphasic kinetic behavior of E. coli WrbA, an FMN-dependent NAD(P)H:quinone oxidoreductase

    Kishko, I., Harish, B., Zayats, V., Reha, D., Tenner, B., Beri, D., Gustavsson, Tobias, Ettrich, R. & Carey, J., 2012, In: PLOS ONE. 7, 8, p. e43902

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: A longitudinal observational study

    Schmiegelow, Christentze, Scheike, Thomas, Oesterholt, M., Minja, D., Pehrson, Caroline, Magistrado, P., Lemnge, M., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., 2012, In: P L o S One. 7, 9, e44773.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria

    Tutterrow, Y. L., Salanti, Ali, Avril, M., Smith, J. D., Pagano, I. S., Ako, S., Fogako, J., Leke, R. G. F. & Taylor, D. W., 2012, In: P L o S One. 7, 6, p. e40049

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high Plasmodium falciparum transmission

    Tutterrow, Y. L., Avril, M., Singh, K., Long, C. A., Leke, R. J., Sama, G., Salanti, Ali, Smith, J. D., Leke, R. G. F. & Taylor, D. W., 2012, In: Infection and Immunity. 80, 4, p. 1479-90 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Identification and characterization of B-cell epitopes in the DBL4e domain of VAR2CSA

    Ditlev, S. B., Nielsen, Morten Agertoug, Resende, M., Agerbæk, Mette Ørskov, Pinto, V. V., Andersen, P. H., Magistrado, P., Lusingu, J., Dahlbäck, M., Theander, Thor Grundtvig & Salanti, Ali, 2012, In: P L o S One. 7, 9, p. e43663

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Marchantin A, a macrocyclic bisbibenzyl ether, isolated from the liverwort Marchantia polymorpha, inhibits protozoal growth in vitro

    Jensen, S., Omarsdottir, S., Bwalya, A. G., Nielsen, Morten Agertoug, Tasdemir, D. & Olafsdottir, E. S., 2012, In: Phytomedicine. 19, 13, p. 1191-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania

    Minja, D. T., Schmiegelow, Christentze, Oesterholt, M., Magistrado, P. A., Boström, S., John, D., Pehrson, C., Andersen, D., Deloron, P., Salanti, Ali, Lemnge, M., Luty, A. J., Alifrangis, Michael, Theander, Thor Grundtvig & Lusingu, J. P., 2012, In: Malaria Journal. 11, 1, p. 211

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania

    Minja, D. T., Schmiegelow, Christentze, Oesterholt, M., Magistrado, P. A., Boström, S., John, D., Pehrson, Caroline, Andersen, D., Deloron, P., Salanti, Ali, Lemnge, M., Luty, A. J., Alifrangis, Michael, Theander, Thor Grundtvig & Lusingu, J. P., 2012, In: Malaria Journal. 11, 211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria

    Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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