Centre for Medical Parasitology

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  1. 2008
  2. Published

    Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum

    Mehlotra, R. K., Mattera, G., Bockarie, M. J., Maguire, J. D., Baird, J. K., Sharma, Y. D., Alifrangis, Michael, Dorsey, G., Rosenthal, P. J., Fryauff, D. J., Kazura, J. W., Stoneking, M. & Zimmerman, P. A., 2008, In: Antimicrobial Agents and Chemotherapy. 52, 6, p. 2212-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dual fluorescence labeling of surface-exposed and internal proteins in erythrocytes infected with the malaria parasite Plasmodium falciparum

    Bengtsson, D. C., Sowa, K. M. P. & Arnot, D. E., 2008, In: Nature Protocols (Print Edition). 3, 12, p. 1990-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effect of a community-based delivery of intermittent preventive treatment of malaria in pregnancy on treatment seeking for malaria at health units in Uganda

    Mbonye, A. K., Schultz Hansen, K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2008, In: Public Health. 122, 5, p. 516-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria

    Adjei, G. O., Kristensen, K., Goka, B. Q., Hoegberg, L. C. G., Alifrangis, Michael, Rodrigues, O. P. & Kurtzhals, J. A. L., 2008, In: Antimicrobial Agents and Chemotherapy. 52, 12, p. 4400-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

    Bejon, P., Lusingu, J., Olotu, A., Leach, A., Lievens, M., Vekemans, J., Mshamu, S., Lang, T., Gould, J., Dubois, M-C., Demoitié, M-A., Stallaert, J-F., Vansadia, P., Carter, T., Njuguna, P., Awuondo, K. O., Malabeja, A., Abdul, O., Gesase, S., Mturi, N. & 9 others, Drakeley, C. J., Savarese, B., Villafana, T., Ballou, W. R., Cohen, J., Riley, E. M., Lemnge, M. M., Marsh, K. & von Seidlein, L., 2008, In: New England Journal of Medicine. 359, 24, p. 2521-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA

    Avril, M., Kulasekara, B. R., Gose, S. O., Rowe, C., Dahlbäck, M., Duffy, P. E., Fried, M., Salanti, Ali, Misher, L., Narum, D. L. & Smith, J. D., 2008, In: Infection and Immunity. 76, 4, p. 1791-800 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    High frequency of Plasmodium falciparum CICNI/SGEAA and CVIET haplotypes without association with resistance to sulfadoxine/pyrimethamine and chloroquine combination in the Daraweesh area, in Sudan

    A-Elbasit, I. E., Khalil, I. F., Elbashir, M. I., Masuadi, E. M., Bygbjerg, Ib Christian, Alifrangis, Michael & Giha, H. A., 2008, In: European Journal of Clinical Microbiology & Infectious Diseases. 27, 8, p. 725-32 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA

    Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Importance of the long-acting partner drug in artemisinin-based combination therapy

    Kurtzhals, Jørgen, 2008, In: Expert Review of Clinical Pharmacology. p. 745-747

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.

    Enattah, N. S., Jensen, T. G. K., Boyd, M., Lewinski, R., Kuokkanen, M., Rasinpera, H., El-Shanti, H., Seo, J. K., Alifrangis, M., Khalil, I. F., Natah, A., Ali, A., Natah, S., Comas, D., Mehdi, S. Q., Groop, L., Vestergaard, E. M., Imtiaz, F., Rashed, M. S., Meyer, B. & 2 others, Troelsen, J. & Peltonen, L., 2008, In: American Journal of Human Genetics. 82, 1, p. 57-72 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Intermittent preventive treatment of malaria in pregnancy: a new delivery system and its effect on maternal health and pregnancy outcomes in Uganda

    Mbonye, A. K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2008, In: Bulletin of the World Health Organization. 86, 2, p. 93-100 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Intermittent preventive treatment of malaria in pregnancy: a community-based delivery system and its effect on parasitemia, anemia and low birth weight in Uganda

    Mbonye, A. K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2008, In: International Journal of Infectious Diseases. 12, 1, p. 22-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Malaria vaccines: immunity, models and monoclonal antibodies

    Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Mosquito abundance, bed net coverage and other factors associated with variations in sporozoite infectivity rates in four villages of rural Tanzania

    Kweka, E. J., Nkya, W. M. M., Mahande, A. M., Assenga, C., Mosha, F. W., Lyatuu, E. E., Massenga, C. P., Nyale, E. M., Mwakalinga, S. B. & Lowassa, A., 2008, In: Malaria Journal. 7, p. 59

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Perceptions of mothers and hospital staff of paediatric care in 13 public hospitals in northern Tanzania

    Mwangi, R., Chandler, C., Nasuwa, F., Mbakilwa, H., Poulsen, A., Bygbjerg, Ib Christian & Reyburn, H., 2008, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 102, 8, p. 805-10 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Prevention and treatment practices and implications for malaria control in Mukono District Uganda

    Mbonye, A. K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2008, In: Journal of Biosocial Science. 40, 2, p. 283-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria

    Wiese, L., Hempel, C., Penkowa, M., Kirkby, N. & Kurtzhals, J. A. L., 2008, In: Malaria Journal. 7, p. 3

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Reduced risk of uncomplicated malaria episodes in children with a+-thalassemia in northeastern Tanzania

    Enevold, A., Lusingu, J. P., Mmbando, B., Alifrangis, Michael, Lemnge, M. M., Bygbjerg, Ib Christian, Theander, Thor Grundtvig & Vestergaard, L. S., 2008, In: American Journal of Tropical Medicine and Hygiene. 78, 5, p. 714-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Risk factors for low birth-weight in areas with varying malaria transmission in Korogwe, Tanzania: implications for malaria control

    Mmbando, B. P., Cole-Lewis, H., Sembuche, S., Kamugisha, M. L., Theander, Thor Grundtvig, Lusingu, J. P. A. & Lemnge, M. M., 2008, In: Tanzania Health Research Bulletin. 10, 3, p. 137-43 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA

    Andersen, P., Nielsen, Morten Agertoug, Resende, M., Rask, T. S., Dahlbäck, M., Theander, Thor Grundtvig, Lund, O. & Salanti, Ali, 2008, In: PLoS Pathogens. 4, 2, p. e42

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

    Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2007
  24. Published

    3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity

    Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

    Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A community-based delivery system of intermittent preventive treatment of malaria in pregnancy and its effect on use of essential maternity care at health units in Uganda

    Mbonye, A. K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2007, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 101, 11, p. 1088-95 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria

    Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  28. Published

    Associations between a+-thalassemia and Plasmodium falciparum malarial infection in northeastern Tanzania

    Enevold, A., Alifrangis, Michael, Sanchez, J. J., Carneiro, I., Roper, C., Børsting, C., Lusingu, J., Vestergaard, L. S., Lemnge, M. M., Morling, Niels, Riley, E. & Drakeley, C. J., 2007, In: Journal of Infectious Diseases. 196, 3, p. 451-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

    Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Complement activation in Ghanaian children with severe Plasmodium falciparum malaria

    Helegbe, G. K., Goka, B. Q., Kurtzhals, Jørgen, Addae, M. M., Ollaga, E., Tetteh, J. K. A., Dodoo, D., Ofori, M. F., Obeng-Adjei, G., Hirayama, K., Awandare, G. A. & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 165

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission

    Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

    Hviid, Lars, 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan

    Ibrahium, A. M., Kheir, M. M., Osman, M. E., Khalil, I. F., Alifrangis, Michael, Elmardi, K. A., Malik, E. M. & Adam, I., 2007, In: Annals of Tropical Medicine and Parasitology. 101, 1, p. 15-21 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Elevated plasma urokinase receptor predicts low birth weight in maternal malaria

    Ostrowski, S. R., Shulman, C. E., Peshu, N., Staalsø, Trine, Høyer-Hansen, G., Pedersen, B. K., Marsh, K. & Ullum, H., 2007, In: Parasite Immunology. 29, 1, p. 37-46 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans

    Enattah, N. S., Trudeau, A., Pimenoff, V., Maiuri, L., Auricchio, S., Greco, L., Rossi, M., Lentze, M., Seo, J. K., Rahgozar, S., Khalil, I., Alifrangis, M., Natah, S., Groop, L., Shaat, N., Kozlov, A., Verschubskaya, G., Comas, D., Bulayeva, K., Mehdi, S. Q. & 7 others, Terwilliger, J. D., Sahi, T., Savilahti, E., Perola, M., Sajantila, A., Järvelä, I. & Peltonen, L., 2007, In: American Journal of Human Genetics. 81, 3, p. 615-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

    Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Intermittent preventive treatment of malaria in pregnancy: evaluation of a new delivery approach and the policy implications for malaria control in Uganda

    Mbonye, A. K., Bygbjerg, Ib Christian & Magnussen, Pascal, 2007, In: Health Policy. 81, 2-3, p. 228-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Intermittent preventive treatment of malaria in pregnancy: the effect of new delivery approaches on access and compliance rates in Uganda

    Mbonye, A. K., Magnussen, Pascal & Bygbjerg, Ib Christian, 2007, In: Tropical Medicine & International Health. 12, 4, p. 519-31 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka

    Schousboe, M. L., Rajakaruna, R. S., Salanti, Ali, Hapuarachchi, H. C., Galappaththy, G. N. L., Bygbjerg, Ib Christian, Amerasinghe, P. H., Konradsen, Flemming & Alifrangis, Michael, 2007, In: Malaria Journal. 6, p. 28

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Laboratory indicators of the diagnosis and course of imported malaria

    Gjørup, I. E., Vestergaard, L. S., Møller, Kirsten, Rønn, A. M. & Bygbjerg, Ib Christian, 2007, In: Scandinavian Journal of Infectious Diseases. 39, 8, p. 707-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Malaria in pregnancy: pathogenesis and immunity

    Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum

    Enevold, A., Nkya, W. M. M. M., Theisen, M., Vestergaard, L. S., Jensen, Anja Ramstedt, Staalsoe, T., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2007, In: Malaria Journal. 6, p. 153

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate

    Shekalaghe, S., Drakeley, C., Gosling, R., Ndaro, A., Meegeren, M. V., Enevold, A., Alifrangis, Michael, Mosha, F., Sauerwein, R. & Bousema, T., 2007, In: PLoS ONE. 2, 10, p. e1023

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Rapid and specific biotin labelling of the erythrocyte surface antigens of both cultured and ex-vivo Plasmodium parasites

    Sharling, L., Sowa, M. P. K., Thompson, J., Kyriacou, H. M. & Arnot, D. E., 2007, In: Malaria Journal. 6, p. Art. No. 66 -

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Responding to the challenge of antimalarial drug resistance by routine monitoring to update national malaria treatment policies

    Vestergaard, L. S. & Ringwald, P., 2007, In: American Journal of Tropical Medicine and Hygiene. 77, 6 Suppl, p. 153-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma

    Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, Lars & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The dog that did not bark: malaria vaccines without antibodies

    Heppner, D. G., Schwenk, R. J., Arnot, D. E., Sauerwein, R. W. & Luty, A. J. F., 2007, In: Trends in Parasitology. 23, 7, p. 293-296 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics

    A-Elbasit, I. E., Alifrangis, Michael, Khalil, I. F., Bygbjerg, Ib Christian, Masuadi, E. M., Elbashir, M. I. & Giha, H. A., 2007, In: Malaria Journal. 6, p. 108

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria

    Hviid, Lars & Salanti, Ali, 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability

    Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2006
  53. Published

    Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

    Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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