CMP > Facilities/technologies
Research facilities and technologies at CMP
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Antibody research
We use antibodies obtained from plasma of Plasmodium falciparum-exposed individuals, from animal immune sera, produced by phage display technology, and produced by B cells or transfected cell lines in vitro.
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Bioinformatics and in silico modeling
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Flow cytometry and cell sorting
We use 4-, 5-, and 7-parameter flow cytometry and fluorescence-activated cell sorting for analysis and selection of cells. In addition, we use magnet-activated cell sorting (Dynal and Miltenyi systems) to select cell subsets.
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Microscopy
We use a variety of microscopic techniques in our research, including light microscopy, phase contrast microscopy, fluorescence microscopy, confocal microscopy, atomic force microscopy, and scanning electron microscopy.
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Parasites
We use P. falciparum parasites isolated from malaria patients with defined clinical syndromes as well as a number of standard laboratory lines and clones. We also use different rodent parasites such as P. berghei and P. chabaudi.
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Recombinant proteins
We use insects and bacteria as expression systems in the production of our recombinant proteins. For the purification we use ÄKTAcrossflow and/or our three ÄKTAxpress systems. We use combinations of different chromatographic methods in our purification.